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NAcM-OPT is a specific, reversible and orally bioavailable inhibitor of cullin neddylation 1 (DCN1) that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM.
| Molecular Weight | 434.4 |
| Formula | C23H29Cl2N3O |
| CAS Number | 2089293-61-6 |
| Solubility (25°C) | DMSO 87 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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