Free shipping on all orders over $ 500

NAB2 

Cat. No. M28546

All AbMole products are for research use only, cannot be used for human consumption.

NAB2  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

NAB2 is a neuron-protective agent. NAB2 strongly and selectively protects diverse cell types from α-syn toxicity. NAB2 promots endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a agentgable node in the biology of α-syn that can correct multiple aspects of its underlying pathology, including dysfunctional endosomal and endoplasmic reticulum-to-Golgi vesicle trafficking.

Chemical Information
Molecular Weight 389.88
Formula C23H20ClN3O
CAS Number 1504588-00-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Edwin B Corgiat, et al. G3 (Bethesda). The Nab2 RNA-binding protein patterns dendritic and axonal projections through a planar cell polarity-sensitive mechanism

[2] Michael E Kallen, et al. Am J Surg Pathol. The 2020 WHO Classification: What's New in Soft Tissue Tumor Pathology?

[3] Ye-Seul Park, et al. Biochem Biophys Res Commun. NAB2-STAT6 fusion protein mediates cell proliferation and oncogenic progression via EGR-1 regulation

[4] Milo B Fasken, et al. Protein Sci. Structure-function relationships in the Nab2 polyadenosine-RNA binding Zn finger protein family

[5] Sayaka Yuzawa, et al. Am J Surg Pathol. Analysis of NAB2-STAT6 Gene Fusion in 17 Cases of Meningeal Solitary Fibrous Tumor/Hemangiopericytoma: Review of the Literature

Related Products
GAPDH-IN-1

GAPDH-IN-1 (GAPDH Inhibitor Compound F8) is a covalent inhibitor of GAPDH (IC50 = 39.31 µM). It viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner.

O-acetylcamptothecin

O-acetylcamptothecin is a derivative of camptothecin, a naturally occurring alkaloid extracted from the bark of the Chinese tree Camptotheca acuminata. Camptothecin and its derivatives are primarily known for their potent anticancer properties, particularly through their action as inhibitors of topoisomerase I, an enzyme critical for DNA replication and transcription.

10-hydroxystearic acid

10-hydroxystearic acid is a hydroxy fatty acid.

SB-T-1214

SB-T-1214 is a new-generation taxoid. SB-T-1214 possesses significant activity against colon cancer spheroids induced by and enriched with drug resistant tumorigenic CD133high/CD44high cells and efficiently inhibited expression of the majority of stem cell-related genes.

NG-497

NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL.

  Catalog
Abmole Inhibitor Catalog




Keywords: NAB2  supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.