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N-Nitroso-N-methylurea

Cat. No. M11369

All AbMole products are for research use only, cannot be used for human consumption.

N-Nitroso-N-methylurea Structure
Synonym:

NMU; MNU; NMH;1-Methyl-1-nitrosourea;N-Methyl-Nnitrosourea;Methylnitrosourea

Size Price Availability Quantity
100mg USD 80  USD80 In stock
250mg USD 140  USD140 In stock
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Quality Control & Documentation
Biological Activity

N-Nitroso-N-methylurea (NMU; MNU; NMH is an effective carcinogenic, mutagenic and teratogenic agent. N-nitroso-n-methylurea is a direct-acting alkylating agent that interacts with DNA. N-nitroso-n-methylurea targets a variety of animal organs to cause various cancers and/or degenerative diseases. N-nitroso-n-methylurea is also a precursor in diazomethane synthesis.

Product Citations
Chemical Information
Molecular Weight 103.08
Formula C2H5N3O2
CAS Number 684-93-5
Solubility (25°C) DMSO ≥ 150 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Keiko Inami, et al. Bioorg Med Chem. Transnitrosation of non-mutagenic N-nitrosoproline forms mutagenic N-nitroso-N-methylurea

[2] No authors listed. Rep Carcinog. N-Nitroso-N-methylurea

[3] National Toxicology Program. Rep Carcinog. N-Nitroso-N-methylurea

[4] C B Huggins, et al. Proc Natl Acad Sci U S A. N-Nitroso-N-methylurea elicits mammary cancer in resistant and sensitive rat strains

[5] No authors listed. IARC Monogr Eval Carcinog Risk Chem Man. N-nitroso-n-methylurea

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Keywords: N-Nitroso-N-methylurea, NMU; MNU; NMH;1-Methyl-1-nitrosourea;N-Methyl-Nnitrosourea;Methylnitrosourea supplier, DNA Alkylator/Crosslinker, inhibitors, activators

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