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Muvalaplin

Cat. No. M40648

All AbMole products are for research use only, cannot be used for human consumption.

Muvalaplin Structure
Synonym:

LY3473329

Size Price Availability Quantity
1mg USD 200  USD200 In stock
5mg USD 450  USD450 In stock
10mg USD 650  USD650 In stock
25mg USD 1100  USD1100 In stock
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Quality Control & Documentation
Biological Activity

Muvalaplin (LY3473329) is a first-in-class, orally active lipoprotein (a) (Lp(a)) inhibitor that inhibits Lp(a) formation by blocking apolipoprotein apo(a)-apo B100 interactions and avoids interaction with the cognate protein fibrinogen. In addition, Muvalaplin is used in the study of cardiovascular and metabolism-related diseases.

Chemical Information
Molecular Weight 710.90
Formula C42H54N4O6
CAS Number 2565656-70-2
Form Solid
Solubility (25°C) DMSO 15 mg/mL (ultrasonic and adjust pH to 3 with 1M HCl)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Stephen J Nicholls et al. JAMA. Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation: A Randomized Clinical Trial

[2] Kartik Gupta et al. Curr Atheroscler Rep. Highlights of Cardiovascular Disease Prevention Studies Presented at the 2023 European Society of Cardiology Congress

  Catalog
Abmole Inhibitor Catalog




Keywords: Muvalaplin, LY3473329 supplier, Lipoprotein (a), inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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