Certificate of Analysis
| Product Name: | Muvalaplin |
| Catalog Number: | M40648 |
| CAS Number: | 2565656-70-2 |
Physical and Chemical Properties
| Formula: | C42H54N4O6 |
| Molecular Weight: | 710.90 |
| Form: | Solid |
| Solubility: | DMSO 15 mg/mL (ultrasonic and adjust pH to 3 with 1M HCl) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Muvalaplin (LY3473329) is a first-in-class, orally active lipoprotein (a) (Lp(a)) inhibitor that inhibits Lp(a) formation by blocking apolipoprotein apo(a)-apo B100 interactions and avoids interaction with the cognate protein fibrinogen. In addition, Muvalaplin is used in the study of cardiovascular and metabolism-related diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |