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MS 21570

Cat. No. M7004

All AbMole products are for research use only, cannot be used for human consumption.

MS 21570 Structure

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Quality Control & Documentation
Biological Activity

MS 21570 is a gPR171 antagonist (IC50 = 220 nM). Inhibits BigLEN (Cat.No. 6304) mediated increases in [35S]GTPγS binding in hypothalamic membranes and hyperpolarization of basolateral amygdala pyramidal neurons. Reduces anxiety-like behavior and fear conditioning in mice.

Chemical Information
Molecular Weight 237.34
Formula C10H11N3S2
CAS Number 65373-29-7
Solubility (25°C) DMSO 23.73 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Puig, et al. Breast Cancer Res. A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines.

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Keywords: MS 21570 supplier, inhibitors, activators

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