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MRTX849 ethoxypropanoic acid

Cat. No. M21518

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MRTX849 ethoxypropanoic acid  Structure
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Biological Activity

MRTX849 ethoxypropanoic acid incorporates a ligand for KRAS G12C, and a PROTAC linker. MRTX849 ethoxypropanoic acid can be used in the synthesis of PROTAC LC-2. LC-2 is a potent, first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50, between 0.25 and 0.76 μM).

Chemical Information
Molecular Weight 720.23
Formula C37H43ClFN7O5
CAS Number 2561529-98-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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m-PEG-OH is a PROTAC linker and belongs to the PEG class. It can be used to synthesize PROTAC molecules.

tert-butyl 4-(3,3-difluoropiperidin-4-yl)piperazine-1-carboxylate

tert-butyl 4-(3,3-difluoropiperidin-4-yl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate

Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

Tert-butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate

Tert-butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.

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Keywords: MRTX849 ethoxypropanoic acid supplier, PROTAC Linker, inhibitors, activators

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