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Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent, it is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
| Molecular Weight | 456.36 |
| Formula | C18H20N2O12 |
| CAS Number | 70539-42-3 |
| Solubility (25°C) | DMSO 90 mg/mL acetic acid: water (1:1): ≤50 mg/mL DMF: soluble |
| Storage | 2-8°C, dry, sealed |
| Related PROTAC Linker Products |
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| 6-Maleimidocaproic Acid
A sulfhydryl reactive heterobifunctional crosslinking reagent. Widely used probe for introducing maleimides groups into biomolecules. A probe for thiol groups in proteins. |
| 5-Ethynyl-2'-deoxyuridine
5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
| Ac4ManNAz (80% α isomer)
Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Ac4ManNAz can be used to selectively modify proteins. Ac4ManNAz can be used in cell labeling, tracking and proteomic analysis. Ac4ManNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. |
| L-Azidohomoalanine hydrochloride
L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
| DSPE-PEG-Biotin (MW 2000)
DSPE-PEG-Biotin (MW 2000) is a PROTAC linker, which belongs to the PEG class. It can be used to synthesize PROTAC molecules. |
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