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EGNHS

Cat. No. M10135

All AbMole products are for research use only, cannot be used for human consumption.

EGNHS Structure
Synonym:

Ethlene Glycol Bis(Succinimidyl Succinate)

Size Price Availability Quantity
50mg USD 40  USD40 In stock
100mg USD 65  USD65 In stock
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Quality Control & Documentation
Biological Activity

Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent, it is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).

Chemical Information
Molecular Weight 456.36
Formula C18H20N2O12
CAS Number 70539-42-3
Solubility (25°C) DMSO 90 mg/mL
acetic acid: water (1:1): ≤50 mg/mL
DMF: soluble
Storage 2-8°C, dry, sealed
References

[1] Yonghan He, et al. J Hematol Oncol. Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

[2] Sainan An, et al. EBioMedicine. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs

[3] Evgeniy V Petrotchenko, et al. Mol Cell Proteomics. Isotopically coded cleavable cross-linker for studying protein-protein interaction and protein complexes

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Keywords: EGNHS, Ethlene Glycol Bis(Succinimidyl Succinate) supplier, PROTAC Linker, inhibitors, activators

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