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MNI-caged-NMDA

Cat. No. M6990

All AbMole products are for research use only, cannot be used for human consumption.

MNI-caged-NMDA Structure

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Quality Control & Documentation
Biological Activity

MNI-caged-NMDA is a NMDA (Cat.No. 0114) caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Stoichiometrically releases chirally pure NMDA. Suitable for uncaging with 300-380 nm excitation. Improved localization can be achieved by uncaging at 405 nm (with mM concentration of caged compound in the bath solution). Exhibits rapid uncaging rate relative to ionotropic glutamate receptor activation.

Chemical Information
Molecular Weight 323.3
Formula C14H17N3O6
CAS Number 1227675-52-6
Solubility (25°C) Water 1.62 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nardou, et al. Front Cell Neurosci. Phenobarbital but not diazepam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus.

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Keywords: MNI-caged-NMDA supplier, inhibitors, activators

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