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ML345 is a potent and selective insulin-degrading enzyme (IDE) small-molecule inhibitor, with an IC50 value of 188 nM. ML345 can be for use as a pharmacophore for agent development in diabetes research.
| Molecular Weight | 479.54 |
| Formula | C21H22FN3O5S2 |
| CAS Number | 1632125-79-1 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] TD Bannister, et al. ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE)
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