Free shipping on all orders over $ 500

ML336 

Cat. No. M28684

All AbMole products are for research use only, cannot be used for human consumption.

ML336  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range.

Chemical Information
Molecular Weight 367.4
Formula C19H21N5O3
CAS Number 1613465-33-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jasper Lee, et al. J Virol. Emergence and Magnitude of ML336 Resistance in Venezuelan Equine Encephalitis Virus Depend on the Microenvironment

[2] Andrew M Skidmore, et al. Antiviral Res. Benzamidine ML336 inhibits plus and minus strand RNA synthesis of Venezuelan equine encephalitis virus without affecting host RNA production

[3] Colleen B Jonsson, et al. Antiviral Res. Efficacy of a ML336 derivative against Venezuelan and eastern equine encephalitis viruses

[4] Annette E LaBauve, et al. Sci Rep. Lipid-Coated Mesoporous Silica Nanoparticles for the Delivery of the ML336 Antiviral to Inhibit Encephalitic Alphavirus Infection

[5] Donghoon Chung, et al. ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV)

Related Anti-infection Products
BTZ043 Racemate

BTZ043 Racemate (BTZ038, BTZ044) is a decaprenylphosphoryl-b-D-ribose 2-epimerase inhibitor.

Enoxacin

Enoxacin is a small molecule inhibitor of binding between the B2-subunit of vacuolar H+-ATPase (V-ATPase) and microfilaments.

Posaconazole

Posaconazole is a sterol C14α demethylase inhibitor with IC50 of 0.25 nM.

Pretomanid

Pretomanid (PA-824) is a novel, orally active nitroimidazole derivative with antimycobacterial activity for use in tuberculosis-related studies.

Clofazimine

Clofazimine is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.

  Catalog
Abmole Inhibitor Catalog




Keywords: ML336  supplier, Anti-infection, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.