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ML 337 is a selective negative allosteric modulator of mGlu3 (IC50 = 593 nM). Displays no activity at mGlu1, mGlu2 or mGlu4-8 at concentrations up to 30 μM. Brain penetrant.
| Molecular Weight | 353.39 |
| Formula | C21H20FNO3 |
| CAS Number | 1443118-44-2 |
| Solubility (25°C) | DMSO 35.34 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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