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Mirvetuximab soravtansine

Cat. No. M40544

All AbMole products are for research use only, cannot be used for human consumption.

Mirvetuximab soravtansine Structure
Size Price Availability Quantity
100ug USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Mirvetuximab soravtansine is an antibody-drug concatenation (ADC) containing a folate receptor alpha (frα)-conjugated antibody, a cleavable junction, and the medenosine alkaloid DM4, a potent microtubulin-targeting agent, that can be used in studies related to platinum-resistant epithelial ovarian cancer (EOC).

Chemical Information
Molecular Weight 977.59
Formula C42H61ClN4O14S3
CAS Number 1453084-37-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lucy Gilbert et al. Gynecol Oncol. Safety and efficacy of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer

[2] Ursula A Matulonis et al. J Clin Oncol. Efficacy and Safety of Mirvetuximab Soravtansine in Patients With Platinum-Resistant Ovarian Cancer With High Folate Receptor Alpha Expression: Results From the SORAYA Study

[3] Young-A Heo. Drugs. Mirvetuximab Soravtansine: First Approval

[4] K N Moore et al. Ann Oncol. Phase III, randomized trial of mirvetuximab soravtansine versus chemotherapy in patients with platinum-resistant ovarian cancer: primary analysis of FORWARD I

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