All AbMole products are for research use only, cannot be used for human consumption.
Miriplatin is a DNA synthesis inhibitor.
In vitro: Miriplatin suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
In vivo: Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
Molecular Weight | 763.99 |
Formula | C34H68N2O4Pt |
CAS Number | 141977-79-9 |
Form | Solid |
Solubility (25°C) | chloroform 30 mg/mL (DMSO can inactivate Miriplatin's activity) |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Related DNA Alkylator/Crosslinker Products |
---|
Illudin S
Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. |
Illudin M
Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. |
Sibiromycin
Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). |
Mitobronitol
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. |
Duocarmycin analog-2
Duocarmycin analog-2 is a potent DNA alkylating agent. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.