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Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A.
| Molecular Weight | 199.63 |
| Formula | C6H14ClNO4 |
| CAS Number | 75172-81-5 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 200 mg/mL |
| Storage | 4°C, dry, sealed |
[2] M Michaud, et al. Rev Med Interne. [Fabry disease: A review]
[3] Sanne J van der Veen, et al. J Inherit Metab Dis. Developments in the treatment of Fabry disease
[4] Emma H McCafferty, et al. Drugs. Migalastat: A Review in Fabry Disease
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