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Methylprednisolone Acetate

Cat. No. M21048

All AbMole products are for research use only, cannot be used for human consumption.

Methylprednisolone Acetate Structure
Synonym:

NSC-19987 acetate, Medrol acetate

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Quality Control & Documentation
Biological Activity

Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.

Chemical Information
Molecular Weight 416.51
Formula C24H32O6
CAS Number 53-36-1
Solubility (25°C) DMSO 86 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Karine Marchioro Leal, et al. Top Companion Anim Med. Is Methylprednisolone Acetate-Related Insulin Resistance Preventable in Cats?

[2] Cheryl Vargo, et al. Vet Dermatol. Is injectable methylprednisolone acetate valuable for treatment of feline hypersensitivity dermatitis?

[3] Kristen I Barton, et al. Inflamm Res. Methylprednisolone acetate mitigates IL1β induced changes in matrix metalloproteinase gene expression in skeletally immature ovine explant knee tissues

[4] Jol Schlatter, et al. Eur Spine J. Safety of intrathecal route: focus to methylprednisolone acetate (Depo-Medrol) use

[5] D A Nelson. Arch Neurol. Dangers from methylprednisolone acetate therapy by intraspinal injection

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Keywords: Methylprednisolone Acetate, NSC-19987 acetate, Medrol acetate supplier, inhibitors, activators

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