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Methyldopa hydrate

Cat. No. M13892

All AbMole products are for research use only, cannot be used for human consumption.

Methyldopa hydrate Structure
Synonym:

L-(-)-α-Methyldopa hydrate; MK-351 hydrate

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Quality Control & Documentation
Biological Activity

Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system.

Chemical Information
Molecular Weight 238.24
CAS Number 41372-08-1
Solubility (25°C) DMSO 33.33 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Michael Durando, et al. Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury

[2] You-Min Tang, et al. [Mechanism and kinetic of methyldopa removal by Fenton's reagent]

[3] M E Schuler, et al. Augmentation of chloral hydrate induced sleep by centrally acting antihypertensive agents

[4] S M Sorensen, et al. 5-HT2 receptor antagonists reverse amphetamine-induced slowing of dopaminergic neurons by interfering with stimulated dopamine synthesis

[5] T M Kenyhercz, et al. High-performance liquid chromatographic assay of isoquinoline alkaloid formation from reaction of biogenic amines and aldehydes

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Keywords: Methyldopa hydrate, L-(-)-α-Methyldopa hydrate; MK-351 hydrate supplier, Adrenergic Receptor, inhibitors, activators

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