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Methyl-β-cyclodextrin

Cat. No. M11339

All AbMole products are for research use only, cannot be used for human consumption.

Methyl-β-cyclodextrin Structure
Synonym:

M-βCD, Methyl-beta-cyclodextrin, M-β-CyD, Methyl-β-CD

Size Price Availability Quantity
500mg USD 30  USD30 In stock
1g USD 40  USD40 In stock
5g USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Methyl-β-cyclodextrin (METHYL-beta-cyclodextrin) is a cycloheptanose that has a solubilizing effect on nonpolar substances and is widely used in the release of hydrophobic drugs. Methyl-β-cyclodextrin is also widely used as a cholesterol lowering agent. Methyl-β-cyclodextrin can significantly reduce clathrin-dependent endocytosis.

Product Citations
Chemical Information
Molecular Weight 1303.3
Formula C54H94O35
CAS Number 128446-36-6
Solubility (25°C) Water 50 mg/mL
DMSO ≥ 60 mg/mL
Storage RT
References

[1] S K Rodal, et al. Mol Biol Cell. Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

[2] Guo Chen, et al. Pharm Biol. Methyl-β-cyclodextrin suppresses the monocyte-endothelial adhesion triggered by lipopolysaccharide (LPS) or oxidized low-density lipoprotein (oxLDL)

[3] Mitsuhiro Abe, et al. J Lipid Res. Imaging cholesterol depletion at the plasma membrane by methyl-β-cyclodextrin

[4] Mahin Rahimi, et al. Poult Sci. The effect of methyl-beta-cyclodextrin on DNA absorption and quality of posttransfected sperm

[5] Z I Krutetskaya, et al. Dokl Biochem Biophys. Methyl-β-cyclodextrin modulates thapsigargin-induced store-dependent Ca 2+ entry in macrophages

[6] Saleemulla Mahammad, et al. Methods Mol Biol. Cholesterol depletion using methyl-β-cyclodextrin

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Keywords: Methyl-β-cyclodextrin, M-βCD, Methyl-beta-cyclodextrin, M-β-CyD, Methyl-β-CD supplier, Solvents & Excipients, inhibitors, activators

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