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Methyl-β-cyclodextrin (METHYL-beta-cyclodextrin) is a cycloheptanose that has a solubilizing effect on nonpolar substances and is widely used in the release of hydrophobic drugs. Methyl-β-cyclodextrin is also widely used as a cholesterol lowering agent. Methyl-β-cyclodextrin can significantly reduce clathrin-dependent endocytosis.
J Virol. 2025 Feb 05.
The Japanese encephalitis virus NS1 protein concentrates ER membranes in a cytoskeleton-independent manner to facilitate viral replication
Methyl-β-cyclodextrin purchased from AbMole
Molecular Weight | 1303.3 |
Formula | C54H94O35 |
CAS Number | 128446-36-6 |
Solubility (25°C) | Water 50 mg/mL DMSO ≥ 60 mg/mL |
Storage | RT |
[6] Saleemulla Mahammad, et al. Methods Mol Biol. Cholesterol depletion using methyl-β-cyclodextrin
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