Free shipping on all orders over $ 500

Methuosis inducer 1 

Cat. No. M25546
Methuosis inducer 1  Structure
Size Price Availability Quantity
5mg USD 285  USD285 In stock
10mg USD 440  USD440 In stock
25mg USD 820  USD820 In stock
50mg USD 1280  USD1280 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Methuosis inducer 1 is a potent methuosis inducer. Methuosis inducer 1 has anticancer activity.

Chemical Information
Molecular Weight 487.48
Formula C27H20F3N5O
CAS Number 2240205-30-3
Form Solid
Solubility (25°C) DMSO 15 mg/mL (ultrasonic and warming and adjust pH to 3 with HCl)
Storage Powder -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Barbara Del Bello, et al. Cancer Cell Int. The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells

[2] Núria Bielsa, et al. Int J Mol Sci. Methuosis Contributes to Jaspine-B-Induced Cell Death

[3] Jun Wu, et al. J Enzyme Inhib Med Chem. Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1 H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent

[4] Claudio D'Amore, et al. Biochim Biophys Acta Mol Cell Res. "Janus" efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms

[5] Hyelim Cho, et al. ACS Omega. Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE

Related Products

Sec61-IN-3 is a protein secretion inhibitor.


Sec61-IN-2 is a protein secretion inhibitor.

Poly(ethylene glycol) diacrylate

Poly(ethylene glycol) diacrylate (PEGDA) is a blank slate hydrogel that gels rapidly at room temperature in the presence of a photoinitiator and light. PEGDA hydrogels are potent tools for uncovering basic cellular biology. PEGDA is an emerging scaffold for tissue engineering and regenerative medicine since polymerization can occur rapidly at room temperature, requires low energy input, has high water content, is elastic, and can be customized to include a variety of biological molecules.


Isothiouronium is a functional group, it is the acid salt of isothiourea.

Sultosilic acid, piperazine salt

Sultosilic acid piperazine salt is a compound with lowering lipid activity. It causes significant shortening of the euglobulin lysis time and a significant diminution of platelet adhesiveness, as well as statistically significant decrease of triglycerides, total cholesterol, beta- and pre-beta-cholesterol and an increase of alpha-cholesterol.

Abmole Inhibitor Catalog

Keywords: Methuosis inducer 1  supplier, inhibitors, activators

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.