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Mesna

Cat. No. M3316

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Mesna Structure
Synonym:

Sodium 2-mercaptoethanesulfonate; Mesnum

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
1g USD 40  USD40 In stock
5g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Mesna (Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.

Chemical Information
Molecular Weight 164.18
Formula C2H5NaO3S2
CAS Number 19767-45-4
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Manuele Casale, et al. MESNA for chemically assisted tissue dissection

[2] I C Shaw, et al. Mesna--a short review

[3] S E Schoenike, et al. Ifosfamide and mesna

[4] K L Dechant, et al. Ifosfamide/mesna. A review of its antineoplastic activity, pharmacokinetic properties and therapeutic efficacy in cancer

[5] M P Goren. Oral mesna: a review

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Keywords: Mesna, Sodium 2-mercaptoethanesulfonate; Mesnum supplier, inhibitors, activators

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