All AbMole products are for research use only, cannot be used for human consumption.
Melflufen (Melphalan flufenamide) hydrochloride, a dipeptide precursor of Melphalan, is an alkylated agent. Melflufen hydrochloride has antitumor activity against multiple myeloma cells and inhibits angiogenesis. Melflufen hydrochloride has irreversible damage to myeloma cell DNA and cytotoxic effects.
| Molecular Weight | 534.88 |
| Formula | C24H31Cl3FN3O3 |
| CAS Number | 380449-54-7 |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related DNA Alkylator/Crosslinker Products |
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| Illudin S
Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. |
| Illudin M
Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. |
| Sibiromycin
Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). |
| Mitobronitol
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol, also known as an anticancer agent that is classified as an alkylating agent. |
| Duocarmycin analog-2
Duocarmycin analog-2 is a potent DNA alkylating agent. |
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