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Meclofenamate sodium is a dual COX-1/COX-2 inhibitor with an IC50 of 40 nM and 50 nM, respectively. used in the study of joint and muscle pain, arthritis, and dysmenorrhea. meclofenamate sodium is a non-selective gap-junction blocker and a highly selective inhibitor of adipose and obesity-associated enzyme (FTO) inhibitor.
| Molecular Weight | 318.13 |
| Formula | C14H11Cl2NO2.Na |
| CAS Number | 6385-02-0 |
| Solubility (25°C) | DMSO 100 mg/mL Water 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Yue Huang, et al. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5
[3] J M Vargyas, et al. Treatment of menorrhagia with meclofenamate sodium
[5] M C Conroy, et al. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium
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