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ME1111 

Cat. No. M28312

All AbMole products are for research use only, cannot be used for human consumption.

ME1111  Structure

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Quality Control & Documentation
Biological Activity

ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research.

Chemical Information
Molecular Weight 202.25
Formula C12H14N2O
CAS Number 1391758-52-3
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Natsuki Kubota-Ishida, et al. Antimicrob Agents Chemother. In Vitro Human Onychopharmacokinetic and Pharmacodynamic Analyses of ME1111, a New Topical Agent for Onychomycosis

[2] Xiaoying Hui, et al. Drug Dev Ind Pharm. Antifungal ME1111 in vitro human onychopharmacokinetics

[3] L Long, et al. Antimicrob Agents Chemother. Evaluation of the Efficacy of ME1111 in the Topical Treatment of Dermatophytosis in a Guinea Pig Model

[4] Sho Takahata, et al. Antimicrob Agents Chemother. Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis

[5] M Ghannoum, et al. Antimicrob Agents Chemother. In vitro antifungal activity of ME1111, a new topical agent for onychomycosis, against clinical isolates of dermatophytes

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Keywords: ME1111  supplier, Antifungal, inhibitors, activators

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