Free shipping on all orders over $ 500

MD-222

Cat. No. M21506

All AbMole products are for research use only, cannot be used for human consumption.

MD-222  Structure
Size Price Availability
5mg USD 950  USD950 Custom Synthesis
10mg USD 1650  USD1650 Custom Synthesis
25mg USD 3450  USD3450 Custom Synthesis
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

MD-222 is a first-in-class, highly effective ProTAC-based MDM2 depressant. MD-222 has anti-cancer properties.

Chemical Information
Molecular Weight 893.83
Formula C48H47Cl2FN6O6
CAS Number 2136246-72-3
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiuling Yang, et al. J Med Chem. Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders

Related Mdm2 Products
MMRi64

MMRi64 disrupts Mdm2-MdmX interactions.

MeOIstPyrd

MeOIstPyrd is an anti-skin cancer agent.

MDM2/XIAP-IN-3

MDM2/XIAP-IN-3 is a dual MDM2/XIAP inhibitor.

UNP-6457

UNP-6457 is a potent active MDM2-p53 interaction inhibitor with an IC50 values of 8.9 nM.

YL93

YL93 is a dual inhibitors of MDM2/4 with Ki values of 0.64 μM and 1.1 nM for MDM4 and MDM2, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: MD-222 supplier, Mdm2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.