Free shipping on all orders over $ 500

LY2881835 

Cat. No. M28122

All AbMole products are for research use only, cannot be used for human consumption.

LY2881835  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

LY2881835 is a potent and selective agonist of G protein-coupled receptor 40 (GPR40). LY2881835 has efficacious and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion. LY2881835 has the potential for the research of type 2 diabetes mellitus.

Chemical Information
Molecular Weight 491.62
Formula C33H33NO3
CAS Number 1292290-38-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Tingting Chen, et al. Eur J Med Chem. Design, synthesis and structure-activity relationship studies of GPR40 agonists containing amide linker

[2] Yanyun Chen, et al. Pharmacol Res Perspect. A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes

[3] Mikhail Krasavin, et al. Eur J Med Chem. Polar aromatic periphery increases agonist potency of spirocyclic free fatty acid receptor (GPR40) agonists inspired by LY2881835

[4] Mikhail Krasavin, et al. Bioorg Med Chem. Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835

Related GPR/FFAR Products
GPR84 antagonist 8 

GPR84 antagonist 8 is a selective GPR84 antagonist.
ML191

ML-191 is an antagonist of GPR55.
CID1172084 

CID1172084 is a selective GPR55 agonist (EC50=0.16 μM).
ML 145 

ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM.
PSN 375963 hydrochloride 

PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively.
  Catalog
Abmole Inhibitor Catalog




Keywords: LY2881835  supplier, GPR/FFAR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.