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LUF6096 

Cat. No. M27806

All AbMole products are for research use only, cannot be used for human consumption.

LUF6096  Structure

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Quality Control & Documentation
Biological Activity

LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.

Chemical Information
Molecular Weight 414.33
Formula C22H21Cl2N3O
CAS Number 1116652-18-6
Form Solid
Solubility (25°C) DMSO 20 mg/mL (ultrasonic and warming and heat to 60°C)
Storage Powder -20°C
References

[1] Lili Du, et al. Purinergic Signal. Species differences and mechanism of action of A3 adenosine receptor allosteric modulators

[2] Lili Du, et al. J Pharmacol Exp Ther. Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor

[3] Kenneth A Jacobson, et al. Adv Pharmacol. Allosteric modulation of purine and pyrimidine receptors

[4] Laura H Heitman, et al. J Med Chem. A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor

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  Catalog
Abmole Inhibitor Catalog




Keywords: LUF6096  supplier, Adenosine Receptor, inhibitors, activators

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