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Administration of lodoxamide tromethamine by inhalation at doses of 0.1 and 1 .O mg uniformly allowed subjects to tolerate significantly larger doses of inhaled allergen extract as measured by the slope, PD, and area under the challenge dose response curve. Lodoxamide at 0.01 mg appeared to be effective in over half the subjects tested. Lodoxamide aerosol was nonirritating and did not act immediately as a bronchodilator.
| Molecular Weight | 553.91 |
| Formula | C11H6N3O6Cl.2[C4H11NO3] |
| CAS Number | 63610-09-3 |
| Form | Solid |
| Solubility (25°C) | 10mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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