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LM2I

Cat. No. M43810

All AbMole products are for research use only, cannot be used for human consumption.

LM2I Structure

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Quality Control & Documentation
Biological Activity

LM2I is a derivative of polymyxin (SPA) and also an activator of argininosuccinate synthase (ASS1), which interacts directly with ASS1 and has antiproliferative and antitumor activities. In addition, LM2I inhibits the growth of colorectal cancer cells through the EGFR pathway. It can be used in studies related to colorectal cancer.

Chemical Information
Molecular Weight 860.13
Formula C47H77N3O11
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kunjian Peng et al. J Nat Prod. Spinosyn A and Its Derivative Inhibit Colorectal Cancer Cell Growth via the EGFR Pathway

[2] Zakaria Ouzerbane et al. Environ Sci Pollut Res Int. Study of the salinity of groundwater in the HAHA syncline by the Kohonen self-organized classification (Essaouira, Morocco)

[3] Zizheng Zou et al. Nat Commun. Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor

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Keywords: LM2I supplier, inhibitors, activators

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