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LIMK-IN-1

Cat. No. M41519

All AbMole products are for research use only, cannot be used for human consumption.

LIMK-IN-1 Structure

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Quality Control & Documentation
Biological Activity

LIMK-IN-1 is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively.

Chemical Information
Molecular Weight 453.34
Formula C20H21BrN8
CAS Number 1116571-01-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, has anti-LIMK1 activity. 8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide has inhibitory property on cell motility.

Curcolonol

Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for LIM kinase 1. Curcolonol can be used for the research of breast cancer.

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CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM.

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CRT0105950 is a potent LIMK inhibitor, with IC50s of 0.3 nM and 1 nM for LIMK1 and LIMK2 respectively. CRT0105950 can be used for the research of cancer.

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TH-257 is a potent and selective allosteric LIMK 1/2 inhibitor with IC50 values of 84 nM and 39 nM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: LIMK-IN-1 supplier, LIM Kinase, inhibitors, activators

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