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Lefamulin acetate

Cat. No. M19869

All AbMole products are for research use only, cannot be used for human consumption.

Lefamulin acetate Structure
Synonym:

BC-3781 acetate

Size Price Availability Quantity
5mg USD 205  USD205 In stock
10mg USD 305  USD305 In stock
25mg USD 500  USD500 In stock
50mg USD 700  USD700 In stock
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Quality Control & Documentation
Biological Activity

Lefamulin acetate (BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.

Chemical Information
Molecular Weight 567.78
Formula C30H49NO7S
CAS Number 1350636-82-6
Solubility (25°C) DMSO 100 mg/mL
Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Matthew William McCarthy. Clin Pharmacokinet. Clinical Pharmacokinetics and Pharmacodynamics of Lefamulin

[2] Todd M Felix, et al. Am Fam Physician. Lefamulin (Xenleta) for the Treatment of Community-Acquired Bacterial Pneumonia

[3] Hung-Jen Tang, et al. Medicine (Baltimore). Lefamulin vs moxifloxacin for community-acquired bacterial pneumonia

[4] No authors listed. Lefamulin

[5] No authors listed. Med Lett Drugs Ther. Lefamulin (Xenleta) for community-acquired bacterial pneumonia

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Keywords: Lefamulin acetate, BC-3781 acetate supplier, Antibiotic, inhibitors, activators

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