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Larsucosterol

Cat. No. M40968

All AbMole products are for research use only, cannot be used for human consumption.

Larsucosterol Structure
Synonym:

DUR-928

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Biological Activity

Larsucosterol is an endogenous sulfated oxysterol and a potent hepatic X receptor (LXR) and DNA methylase (DNMTS) antagonist that regulates endogenous lipogenesis as well as inhibits cholesterol biosynthesis by lowering mRNA levels and inhibiting SREBP-1 activation. May be used in studies related to psoriasis.

Chemical Information
Molecular Weight 482.72
Formula C27H46O5S
CAS Number 884905-07-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tarek Hassanein et al. Am J Gastroenterol. Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis

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Keywords: Larsucosterol, DUR-928 supplier, Liver X Receptor, inhibitors, activators

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