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Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with IC50s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hydrochloride exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil can be used for the research of depression and Alzheimer's disease.
| Molecular Weight | 308.8 |
| Formula | C16H21ClN2O2 |
| CAS Number | 209394-18-3 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Monoamine Oxidase Products |
|---|
| Clorgyline
Clorgyline (M&B 9302) is an orally active, blood-brain barrier permeable and selective monoamine oxidase A (MAO-A) inhibitor. |
| MAO-B-IN-2
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively. |
| Befloxatone
Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). |
| Moclobemide N-Oxide
Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. |
| Indazole
Indazole, also called isoindazole, a heterocyclic aromatic organic compound. |
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