Free shipping on all orders over $ 500

L-Thyroxine sodium salt pentahydrate

Cat. No. M5759
L-Thyroxine sodium salt pentahydrate Structure

Sodium levothyroxine pentahydrate

Size Price Availability Quantity
500mg USD 60  USD60 In stock
1g USD 78  USD78 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

L-thyroxine sodium salt pentahydrate (L-thyroxine sodium pentahydrate; Levothyroxine, both found to lower total and LDL cholesterol levels. L-Thyroxine sodium salt pentahydrate (Levothyroxine;  T4) is a synthetic thyroid hormone used in the study of hypothyroidism.

Chemical Information
Molecular Weight 888.93
Formula C15H20I4NNaO9
CAS Number 6106-07-6
Form Solid
Solubility (25°C) 28 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Karp WB, et al. Pediatr Res. The effect of hydrocortisone, thyroxine, and phenobarbital on diamine oxidase activity in newborn rat intestine.

Related Thyroid Hormone Receptor Products

ZYT-1 is a thyroid receptor (THR-β) agonist.


VK-0214 is an orally active, selective small molecule agonist of the thyroid receptor (THR-β) for studies related to X-linked adrenoleukodystrophy (X-ALD) and hyperlipidemia.


PF-00277343 is a selective thyroid receptor (THR-β) agonist.

Parathyroid Hormone (1-34), bovine

Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist.

(D-Trp12, Tyr34)-pTH (7-34) amide (bovine)

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane.

Abmole Inhibitor Catalog

Keywords: L-Thyroxine sodium salt pentahydrate, Sodium levothyroxine pentahydrate supplier, Thyroid Hormone Receptor, inhibitors, activators

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.