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L-carnitine

Cat. No. M3580
L-carnitine Structure
Synonym:

Levocarnitine

Size Price Availability Quantity
500mg USD 45  USD45 In stock
5g USD 60  USD60 In stock
10g USD 105  USD105 In stock
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Quality Control & Documentation
Biological Activity

L-carnitine is present in striated muscle and liver and is used in studies of hyperlipoproteinemia, stimulating gastric and pancreatic secretions.

Chemical Information
Molecular Weight 161.2
Formula C7H15NO3
CAS Number 541-15-1
Solubility (25°C) DMSO 10mg/mL
Water 30mg/mL
Ethanol 30 mg/mL
Storage 4°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ashok Agarwal, et al. Role of L-carnitine in female infertility

[2] Gustavo C Ferreira, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain

[3] M Pooyandjoo, et al. The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials

[4] Jolanta Pekala, et al. L-carnitine--metabolic functions and meaning in humans life

[5] Charles J Rebouche. Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism

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Keywords: L-carnitine, Levocarnitine supplier, Estrogen Receptor, inhibitors, activators


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