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L-365260

Cat. No. M7890

All AbMole products are for research use only, cannot be used for human consumption.

L-365260 Structure

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Quality Control & Documentation
Biological Activity

L-365260 is a CCK2 selective antagonist. Enhances amphetamine-induced stimulation of locomotor activity in rats (a model of drug abuse), inhibits thyroid carcinoma (TT)-cell proliferation (potential therapeutic implication for cancer treatment); bilateral injection into the medulla reverses both tactile allodynia and thermal hyperalgesia.

Chemical Information
Molecular Weight 398.46
Formula C24H22N4O2
CAS Number 118101-09-0
Solubility (25°C) DMSO: ≥20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Luis Enrique Chaparro, et al. Combination pharmacotherapy for the treatment of neuropathic pain in adults

[2] Dan Li, et al. Effect of gastrin on tyrosine phosphorylation of focal adhesion kinase in human gastric cancer cell line SGC7901

[3] M Bays, et al. Gateways to clinical trials

[4] J Dunlop. CCK receptor antagonists

[5] V Matto, et al. The effects of cholecystokinin A and B receptor antagonists, devazepide and L 365260, on citalopram-induced decrease of exploratory behaviour in rat

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Abmole Inhibitor Catalog




Keywords: L-365260 supplier, inhibitors, activators

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