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KMN-80 

Cat. No. M28725

All AbMole products are for research use only, cannot be used for human consumption.

KMN-80  Structure

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Quality Control & Documentation
Biological Activity

KMN-80, a derivative of PGE1, is a selective and potent agonist of EP4 receptor with an IC50 and a Ki of 3 nM and 2.35 nM, respectively. KMN-80 is against EP3 receptor with an IC50 of 1.4 μM and >10 μM for all other prostanoid receptors.

Chemical Information
Molecular Weight 363.49
Formula C21H33NO4
CAS Number 1628759-75-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Stephen D Barrett, et al. J Med Chem. Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE1 Series EP4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE1 Analog (KMN-159) as a Potent EP4 Agonist

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  Catalog
Abmole Inhibitor Catalog




Keywords: KMN-80  supplier, Prostaglandin Receptor, inhibitors, activators

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