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Ki-7 is an A2B adenosine receptor positive allosteric regulator. Ki-7 enhances cAMP accumulation induced by NECA, a non-selective A2B adenosine receptor agonist (EC50=445.8 nM). Ki-7 also enhanced selective A2B adenosine receptor agonist BAY 60-6583 and adenosine-induced cAMP accumulation with EC50 of 2390 nM and 2550 nM, respectively.
| Molecular Weight | 354.41 |
| Formula | C23H18N2O2 |
| CAS Number | 1489263-00-4 |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Irma Nareswari, et al. Med Acupunct. Acupuncture Therapy for Severe Oligoasthenoteratozoospermia
| Related Adenosine Receptor Products |
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| CV1808
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively. |
| FK 453
FK 453 is a potent and selective adenosine A1 receptor antagonist with an IC50 value of 17.2 nM. |
| GS-9667
GS-9667 (CVT 3619), a novel N6-5'-substituted adenosine analog, is a selective, partial agonist of the A1 adenosine receptor (A1AdoR). |
| PD81723
PD81723 is an adenosine receptor binding enhancer. |
| PSB-0788
PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. |
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