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JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.
| Molecular Weight | 277.75 |
| Formula | C14H16ClN3O |
| CAS Number | 459168-41-3 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Robin L Thurmond, et al. Clinical Development of Histamine H 4 Receptor Antagonists
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