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JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
Molecular Weight | 398.89 |
Formula | C21H23ClN4O2 |
CAS Number | 1610536-69-0 |
Form | Solid |
Solubility (25°C) | DMSO ≥ 250 mg/mL (ultrasonic and warming and heat to 60°C) |
Storage | 4°C, dry, sealed |
[1] Chuangchuang Xu, et al. Org Biomol Chem. Metal-free and regiospecific synthesis of 3-arylindoles
[3] No authors listed. Carteolol
[5] S Groszkowski, et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines
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