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JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
| Molecular Weight | 398.89 |
| Formula | C21H23ClN4O2 |
| CAS Number | 1610536-69-0 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 150 mg/mL (ultrasonic) Water ~2 mg/mL (ultrasonic and heat to 50°C) |
| Storage | 4°C, dry, sealed |
[1] Chuangchuang Xu, et al. Org Biomol Chem. Metal-free and regiospecific synthesis of 3-arylindoles
[3] No authors listed. Carteolol
[5] S Groszkowski, et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines
| Related MELK Products |
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| OTSSP167 hydrochloride
OTSSP167 hydrochloride is a highly potent, selective MELK inhibitor with IC50 of 0.41 nM. |
| JNJ-47117096
JNJ-47117096 is potent and selective MELK inhibitor with IC50 of 23 nM. |
| MELK-8a hydrochloride
MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM. |
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