Certificate of Analysis

 

Product Name: JNJ-47117096 hydrochloride
Catalog Number: M28669
CAS Number: 1610536-69-0

Physical and Chemical Properties
Formula: C21H23ClN4O2
Molecular Weight: 398.89
Form: Solid
Solubility: DMSO ≥ 250 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: 4°C, dry, sealed
Chemical Structure: JNJ-47117096 hydrochloride Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.