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JBSNF-000088 (6-Methoxynicotinamide)

Cat. No. M9681

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JBSNF-000088 (6-Methoxynicotinamide) Structure
Synonym:

6-Methoxynicotinamide

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100mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide (NA) analogue, which is a potent NNMT inhibitor. Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide n-methyl transferase (NNMT) inhibitor. The IC50 of monkey NNMT and mouse NNMT were 1.8 µM, 2.8 µM and 5.0 µM, respectively. In animal models of metabolic diseases, JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization and regulates glucose.

Chemical Information
Molecular Weight 152.15
Formula C7H8N2O2
CAS Number 7150-23-4
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Aimo Kannt, et al. Sci Rep. A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

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Keywords: JBSNF-000088 (6-Methoxynicotinamide), 6-Methoxynicotinamide supplier, inhibitors, activators

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