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Izencitinib

Cat. No. M10837

All AbMole products are for research use only, cannot be used for human consumption.

Izencitinib  Structure
Synonym:

TD-1473

Price and Availability

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Quality Control & Documentation
Biological Activity

Izencitinib (TD-1473) is an orally active, non-selective, gut-limited pan-JAK inhibitor. It may be used in studies related to inflammatory bowel disease (IBD).

Chemical Information
Molecular Weight 402.5
Formula C22H26N8
CAS Number 2051918-33-1
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rhiannon N Hardwick, et al. Toxicol Sci. Gut-Selective Design of Orally-Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species

[2] Giulia Roda, et al. Expert Rev Gastroenterol Hepatol. JAK selectivity: more precision less troubles

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  Catalog
Abmole Inhibitor Catalog




Keywords: Izencitinib , TD-1473 supplier, JAK, inhibitors, activators

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