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Cat. No. M20909
Isoprinosine Structure

inosine pranobex, Immunovir, Groprinosin, Delimmun

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Biological Activity

Isoprinosine is an immunopharmacologic agent with antiviral activities.

Chemical Information
Molecular Weight 1115.23
Formula C52H78N10O17
CAS Number 36703-88-5
Solubility (25°C) DMSO 100 mg/mL
Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Jiri Sliva, et al. Adv Ther. Inosine Pranobex: A Key Player in the Game Against a Wide Range of Viral Infections and Non-Infectious Diseases

[2] A Vţă. Rev Med Chir Soc Med Nat Iasi. [Isoprinosine]

[3] P R Huttenlocker. Ann Neurol. Isoprinosine therapy and SSPE

[4] D P Addy. Neurology. Isoprinosine in SSPE

[5] G Renoux, et al. J Immunopharmacol. Isoprinosine as an immunopotentiator

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Keywords: Isoprinosine, inosine pranobex, Immunovir, Groprinosin, Delimmun supplier, Anti-infection, inhibitors, activators

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