All AbMole products are for research use only, cannot be used for human consumption.
For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.
Iscalimab (CFZ-533) is a non-depleting IGg1 monoclonal antibody targeting CD40 (KD: 0.3 nM). Iscalimab can be used for research of Graves' hyperthyroidism and autoimmune diseases.
| CAS Number | 2031153-61-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Luigi Bartalena, et al. J Intern Med. Current concepts regarding Graves' orbitopathy
[2] Bin Wang, et al. BioDrugs. Targeted Therapy for Primary Sjögren's Syndrome: Where are We Now?
[3] Ondrej Viklicky, et al. Curr Opin Organ Transplant. Developments in immunosuppression
[4] Clio P Mavragani, et al. J Autoimmun. Sjögren's syndrome: Old and new therapeutic targets
| Related TNF Receptor Products |
|---|
| Ozekibart
Ozekibart is an anti-TNFRSF10B monoclonal antibody. |
| TAPI-0
TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. |
| Semapimod tetrahydrochloride
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. |
| BMS-566394
BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE). |
| APVO603
APVO603 is a dual agonist bispecific antibody employing a novel mechanism of action to simultaneously target 4-1BB (CD137) and OX40 (CD134), both members of the TNF-receptor family. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
