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IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo.
| Molecular Weight | 573.68 |
| Formula | C36H35N3O4 |
| CAS Number | 169545-27-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related Endothelin Receptor Products |
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