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INY-03-041 is an effective and highly selective Protac-based pan-Akt degradation consisting of GDC-0068, an ATP-competitive AKT inhibitor conjugated to lenalidomide (Cereblon ligand). INY-03-041 inhibited AKT1, AKT2 and AKT3 with IC50 values of 2.0 nM, 6.8 nM and 3.5 nM, respectively.
| Molecular Weight | 798.41 |
| Formula | C44H56ClN7O5 |
| CAS Number | 2503017-97-6 |
| Solubility (25°C) | DMSO : 115 mg/mL |
| Storage | -20°C, dry, sealed |
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