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Inarigivir

Cat. No. M30140

All AbMole products are for research use only, cannot be used for human consumption.

Inarigivir Structure
Synonym:

ORI-9020; SB-9000

Size Price Availability Quantity
1mg USD 250  USD250 In stock
5mg USD 500  USD500 In stock
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Quality Control & Documentation
Biological Activity

Inarigivir (ORI-9020) is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as a RIG-I agonist to activate cellular innate immune responses.

Chemical Information
Molecular Weight 587.5
Formula C20H26N7O10PS
CAS Number 475650-36-3
Form Solid
Solubility (25°C) DMSO 200 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charles J Zhang, et al. J Hepatol. A human liver organoid screening platform for DILI risk prediction

[2] Man-Fung Yuen, et al. Liver Int. A phase 2, open-label, randomized, multiple-dose study evaluating Inarigivir in treatment-naïve patients with chronic hepatitis B

[3] Arshad Khan, et al. Front Immunol. NOD2/RIG-I Activating Inarigivir Adjuvant Enhances the Efficacy of BCG Vaccine Against Tuberculosis in Mice

[4] Elise J Smolders, et al. Aliment Pharmacol Ther. Review article: clinical pharmacology of current and investigational hepatitis B virus therapies

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Keywords: Inarigivir, ORI-9020; SB-9000 supplier, Anti-infection, inhibitors, activators

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