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Inarigivir soproxil

Cat. No. M9530

All AbMole products are for research use only, cannot be used for human consumption.

Inarigivir soproxil Structure
Synonym:

SB 9200

Size Price Availability Quantity
10mM*1mL in DMSO USD 600  USD600 In stock
5mg USD 390  USD390 In stock
10mg USD 580  USD580 In stock
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Quality Control & Documentation
Biological Activity

Inarigivir soproxil shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. Inarigivir soproxil has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus, and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.

Chemical Information
Molecular Weight 703.62
Formula C25H34N7O13PS
CAS Number 942123-43-5
Solubility (25°C) DMSO ≥ 70 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Arshad Khan, et al. Front Immunol. NOD2/RIG-I Activating Inarigivir Adjuvant Enhances the Efficacy of BCG Vaccine Against Tuberculosis in Mice

[2] Meleri Jones, et al. J Med Virol. SB 9200, a Novel Agonist of Innate Immunity, Shows Potent Antiviral Activity Against Resistant HCV Variants.

[3] Manasa Suresh, et al. PLoS One. Antiviral Efficacy and Host Immune Response Induction During Sequential Treatment With SB 9200 Followed by Entecavir in Woodchucks.

[4] Kyle E Korolowicz, et al. PLoS One. Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

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Keywords: Inarigivir soproxil, SB 9200 supplier, HCV Protease, inhibitors, activators

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