Free shipping on all orders over $ 500

Imeglimin

Cat. No. M30598

All AbMole products are for research use only, cannot be used for human consumption.

Imeglimin Structure
Synonym:

EMD 387008

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Imeglimin (EMD 387008) is an oral glucose-lowering agent. Imeglimin improves insulin sensitivity. Imeglimin also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA and improves mitochondrial function.

Chemical Information
Molecular Weight 155.2
Formula C6H13N5
CAS Number 775351-65-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jessica Huston, et al. Drugs Today (Barc). Imeglimin in type 2 diabetes

[2] Jinghe Li, et al. Diabetes. Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway

[3] Yvette N Lamb. Drugs. Imeglimin Hydrochloride: First Approval

[4] Sophie Hallakou-Bozec, et al. Diabetes Obes Metab. Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes

[5] Raghunandan Yendapally, et al. Drug Dev Res. A review of phenformin, metformin, and imeglimin

Related Mitochondrial Related Products
OPC-163493

OPC-163493 is an orally active and liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces the production of mitochondrial Δψ and ROS.

Mitochondrial fusion promoter M1

Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 (2 mg/kg; iv) alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury.

NL-1

NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50 values of 47.35 μM and 56.26 μM, respectively.

Malonyl CoA lithium

Malonyl CoA lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). Malonyl Coenzyme A lithium (Malonyl CoA lithium) is an important precursor for the production of a variety of chemicals that modulate insulin-stimulated glucose transport in myotubes. Malonyl Coenzyme A is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane.

MFI8 

MFI8 is a small molecule inhibitor of mitochondrial.

  Catalog
Abmole Inhibitor Catalog




Keywords: Imeglimin, EMD 387008 supplier, Mitochondrial Related, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.