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IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
| Molecular Weight | 337.46 |
| Formula | C19H15NOS2 |
| CAS Number | 307525-40-2 |
| Solubility (25°C) | DMSO: ≥25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Juho Suojanen, et al. AlphaMbeta2 integrin modulator exerts antitumor activity in vivo
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